Laboratory Phone: (787)764-0000 Ext. 3220
Ph.D. 1989 from Texas A&M University
Postdoc 1989-1990 from Texas A&M University
NSF Postdoc 1990-1992 from California Institute of Technology
Inorganic, bioinorganic, and materials chemistry; Layered inorganic compounds; Artificial photosynthesis; Amperometric biosensors; Drug delivery systems; Photophysics and photochemistry of luminescent metal complexes.
We focus our research efforts on the use of layered inorganic materials in applications ranging from artificial photosynthesis, amperometric biosensors, vapochromic materials, and drug delivery systems. We make use of X-ray powder diffraction methods, UV-vis spectrophotometry, luminescence spectroscopy and lifetime measurements, X-ray photoelectron, NMR and IR spectroscopies, and electrochemical methods to characterize and study our materials.
As global warming and climate change dramatize the urgent need to switch to sustainable carbon-free energy sources we are pursuing an artificial photosynthesis project in which excited state electron donors are being intercalated in zirconium phosphate layered materials and reacted with suitable quenchers to provoke long-lived charge separation as a way to mimic the primary processes of photosynthesis and develop cheap, efficient, solar cells.
Amperometric biosensors are being prepared by modifying electrodes with zirconium phosphates intercalated with electron mediators based on ruthenium, iron, and cobalt complexes for sensing substrates such as ethanol and lactate.
Platinum terpyridyl complexes intercalated in zirconium phosphate are the basis of our project aimed at developing vapochromic and vapoluminescent materials for detection of volatile organic compounds.
Biohybrid materials based on intercalated drugs such as cisplatin and insulin are being developed in a biomedicine project aimed at selectively delivering bioactive agents to intended biological targets using layered nanoparticles.
"Collaborations for several of these projects are currently in place with researchers at the University of Cincinnati, Texas A&M University, University of Nantes (France), and the University of Puerto Rico -Río Piedras, Mayagüez, and Medical Sciences campuses. In addition, we are part of the Caribbean Brigade of the Solar Army, the outreach program of the NSF sponsored Center for Chemical Innovation-Solar Fuels in collaboration with Caltech. The Caribbean Brigade has given workshops on solar energy to hundreds of teachers and thousands of students in Puerto Rico
Selected Recent Publications
"Drug Carriers Based on Zirconium Phosphates Nanoparticles”, Colón, J. L.; Casañas, B. in Tailored Organic-Inorganic Materials, Brunet, E.; Colón, J. L.; Clearfield, A. Eds., Wiley: Hoboken, 2015.
“Molybdocene dichloride intercalation into zirconium phosphate nanoparticles”, Casañas-Montes, B.; Díaz, A.; Barbosa, C.; Ramos, C.; Collazo, C.; Meléndez, E.; Queffelec, C.; Fayon, F.; Clearfield, A.; Bujoli, B.; Colón, J. L., J. Organomet. Chem. 2015, 791, 34-40.
“Zirconium Phosphate Nanoplatelet Potential for Anticancer Drug Delivery Applications”, González, M. L.; Ortiz, M.; Hernández, C.; Cabán, J.; Rodríguez, A.; Colón, J. L.; Báez, A.. J. Nanosci. Nanotech. 2015, in press.
“Direct Intercalation of Cisplatin into Zirconium Phosphate Nanoplatelets for Potential Cancer Nanotherapy”, Agustín Díaz, Riviam J. Pérez, Amanda David, Millie L. González, Adriana Báez Tiffany B. Kinnibrugh, Paul Zhang, Abraham Clearfield, and Jorge L. Colón,Nanoscale 2013, 5, 11456-11463.
“Zirconium phosphate nano-platelets: a novel platform for drug delivery in cancer therapy”, Agustín Díaz, Vipin Saxena, Julissa González, Amanda David, Barbara Casañas, James D. Batteas, Jorge L. Colón, Abraham Clearfield, and M. Delwar Hussain, Chem. Commun. 2012, 48, 1754-1756.
“Direct Intercalation of Bis-2,2’,2”,6-terpyridyl Cobalt (III) into Zirconium Phosphate Layers for Biosensing Applications”,Mitk’El B. Santiago-Berríos, Chasterie Declet-Flores, Amanda David, Solmarie Borrero, Meredith M. Vélez, Agustín Díaz-Díaz, Ana R. Guadalupe and Jorge L. Colón, Langmuir 2012, 28, 4447-4452
“Luminescence Rigidochromism and Redox Chemistry of Pyrazolate-Bridged Binuclear Platinum(II) Diimine Complex Intercalated into Zirconium Phosphate Layers”, Eladio J. Rivera, Cindy Barbosa, Rafael Torres, Harry Rivera, Estevao R. Fachini, Tyler W. Green, and William B. Connick, and Jorge L. Colón, Inorg. Chem. 2012, 51, 2777-2784.
Eladio J. Rivera, Cindy Barbosa, and Rafael Torres, Levi Grove, Stephen Taylor, and William B. Connick, Abraham Clearfield, and Jorge L. Colón, "Vapochromic and Vapoluminescence Response of Materials based on Platinum(II) Complexes intercalated into Layered Zirconium Phosphate", J. Mater. Chem. 2011, 21, 15899-15902.
Tailored Organic-Inorganic Materials, Brunet, E.; Colón, J. L.; Clearfield, A. Eds., Wiley: Hoboken, 2015.
El proyecto de explotación minera en Puerto Rico (1962-1968): Nacimiento de la conciencia ambiental moderna, Colón, J. L.; Córdova Iturregui, F; Córdova Iturregui, J. Ediciones Huracán: Río Piedras, 2014.