Vilmalí López-Mejías

Zhongfang ChenAssistant Professor

Office: FB 123
E-mail: vilmali.lopez@upr.edu
Phone: (787) 764-0000

Education

2011 Ph.D. in Analytical Chemistry from the University of Michigan-Ann Arbor under the advising of Adam J. Matzger

2008 M.S. in Analytical Chemistry from the University of Michigan-Ann Arbor under the advising of Adam J. Matzger

2006 B.S. in Chemistry from the University of Puerto Rico-Río Piedras

Postdoc

2011-2013 Post-Doctoral Associate in Chemical Engineering at the Massachusetts Institute of Technology under the supervision of Allan S. Myerson and Bernhardt L. Trout

Teaching Experience

2013-2014 Visiting Assistant Professor of Chemistry at Washington and Lee University, Lexington VA.

Research interests

Our research is focused in understanding heterogeneous nucleation mechanisms in order to control crystallization outcomes of industrially relevant materials. Our group works to design heteronucleation platforms and apply these in three major crystallization efforts: to gain understanding of the fundamental factors that affect nucleation in molecular compounds, to promote or inhibit heterogeneous nucleation, and to access, stabilize and deliver solid-forms for novel applications.

Publications

Vilmalí López-Mejías, Jeff W. Kampf, Adam J. Matzger, “Polymer-Induced Heteronucleation of Tolfenamic Acid: Structural Investigation of a Pentamorph,” J. Am. Chem. Soc., 2009, 131, 4554.

Arthur A. McClelland, Vilmalí López-Mejías, Adam J. Matzger, Zhan Chen, “Peering at a Buried Polymer-Crystal Interface: Probing Heterongeneous Nucleation by Sum Frequency Generation Vibrational Spectroscopy,” Langmuir, 2011, 27, 2162–2165.

Vilmalí López-Mejías, Jennifer L. Knight, Charles L. Brooks III, Adam J. Matzger, “On the Mechanism of Polymorph Selection by Polymer Heteronuclei,” Langmuir, 2011, 27, 7575–7579.

Vilmalí López-Mejías, Jeff W. Kampf, Adam J. Matzger, “Nonamorphism in Flufenamic acid and a New Record for a Polymorphic Compound with Solved Structures,” J. Am. Chem. Soc., 2012, 134, 9872-9875.

Vilmalí López-Mejías, Allan S. Myerson, Bernhardt L. Trout, “Geometric Design of Heterogeneous Nucleation Sites on Biocompatible Surfaces” Cryst. Growth & Des. 2013, 13, 3835−3841.

Efrem Curcio, Vilmalí López-Mejías, Gianluca Di Profio, Enrica Fontananova, Enrico Drioli, Bernhardt L. Trout Allan S. Myerson, “Regulating Nucleation Kinetics Through Molecular Interactions at the Polymer-Solute Interface” Cryst. Growth & Des. 2014, 14, 678-686.

Vilmalí López-Mejías,  Burak H. Eral, Patrick S. Doyle, Allan S. Myerson, Bernhardt L. Trout,  “Towards Control of Nucleation and Encapsulation with Alginate Hydrogels: A Biocompatible Vehicle for Hydrophilic and Hydrophobic Drugs ” Cryst. Growth & Des. 2014, 14, 2073–2082.

Patent

Huseyin Burak Eral, Vilmalí López-Mejías, Allan Stuart Myerson, Bernhardt Levy Trout, Patrick S. Doyle, and Marcus O'Mahony “Polymer Matrices for Controlling Crystallization” Provisional Patent No. 61/917,554, Dec. 18, 2013.