The Department of Chemistry is located in the College of Natural Sciences of the University of Puerto Rico, Rí­o Piedras Campus. It is accredited by the American Chemical Society and by the Middle States Association of Universities and Colleges.

The department has a permanent teaching faculty of 27 (in tenured or tenure-track posistions), 17 of which are active researchers in the following areas: electrochemistry, organic synthesis, crystallography, photochemistry, biochemistry, bioinorganic chemistry, laser spectroscopy, marine natural products, theoretical chemistry and environmental analytical chemistry.